RonR's comment is the best answer in this thread. It's all about the tire supporting the load it's carrying. Less load = less pressure. More load = more pressure. Wrong pressure = uneven tire wear. Too high is less of an evil than too low, which can overheat and destroy the tire, but even then you're throwing away tire life. If you vary the load greatly, you need to change the pressure. Running the pressure listed on the sidewall is at max load. No need to do that, unless you are at max load. The pressure listed on the door jamb placard is a good place to start, but might not be optimum. After putting 318K and 360K miles on my previous two vans, gas E150 and diesel E350 respectively, I eventually found optimum tire pressures for each and they were vastly different.
One more anecdote to share: For years, we'd summer vacation caravan with a few friends and I got to know all too well what the ass-end of their vehicles looked like. Behind one friend, after a few days on the road, I noticed that the rear tires of his dually rig seemed to be bulging and touching each other at the ground. This suggested they were underinflated. He repeatedly checked the tire pressure [pencil gauge I believe?] and all seemed good. After about a week, he had a tire go flat. Turns out all four dually tires were trashed because they had been underinflated and rubbed each other to death, on the inside sidewalls. His tire gauge was incorrectly [but consistently precise] reading way too high. Guess the lesson is confirm you tire gauge accuracy.
The correct pressure for your total weight per vheel is whatever pressure will give you even wear across the tread. If it wears more on the edges it is under inflated and if more in the center it is over inflated. The other way is to do a fairly straight drive long enough to warm the tires. If hotter in the center compared to the sides it is over inflated.
I'm at 3600lbs front and 4600lbs in back and found that at 70 the back was slightly under inflated for my LTX245/75 tires. This link:
https://www.michelintruck.com/assets/pdf/Truck_Tire_Data_Book_Sept2011.pdf
...snip...
Ron