In the winter, I run K02s on the front and 4 studded tires on the duallys. I have an Eaton Truetrac LSD. (225/75/16s)
In town driving: With this set-up I have had no issues and the van handles about as good as comparable pick-ups and other dually RWD vehicles. Does pretty good on ice in town,
On Freeways and highways while it is snowing: No issues to date. Van drives well on fresh snow without long term ice that has built up on the road.
Up and down 2-lane mountain roads: Going up hill has been fine, but going downhill on slicker roads, or where Ice is starting build up in shaded road sections due to a day of traffic driving on the road, I have had a few hair raising experiences. Primarily because in early winter when the first storms hit, I usually forget to load up the back of the van with sand bags. Therefore while driving downhill, the CG shifts forward enough to make the rear-end lighter , therefore the back end has the tendency to pop out in the back. (I have had a couple situations where I started breaking on a straight downhill only to have the rear-end start to drift to one side or the other.)
Therefore I have to remember to put 300 to 500 lbs in the back in order to get proper traction. (Mine is a wagon without the seats in the back, so this makes it even lighter.)